Nndevelopment of junctional epithelium pdf

The term junctional epithelium denotes the tissue that is affixed to the tooth on one side and to the oral sulcular epithelium and connective tissue on the other side 17, 100. Apoptosis occurs in the border between oral and reduced enamel epithelia during tooth eruption. Junctional epithelium je, which is derived from odontogenic epithelial cells immediately after eruption, is believed to be gradually replaced by oral gingival epithelium oge over a lifetime. Neither group showed significant changes in location of the apical cells of the attachment epithelium. Knowledge of factors contributing to the initiation and progression of pocket formation is important and may result in the development of better preventive measures and improve healing outcomes after therapeutic interventions. The junctional epithelium is located at a strategically important interface between the gingival sulcus, populated with bacteria, and the periodontal soft and mineralized connective tissues that need protection from becoming exposed to bacteria and. Junctional epithelium, is that epithelium which lies at the base of gingival sulcus. Prior to the emergence of the tooth into the oral cavity, the enamel surface is. The junctional epithelium je adjacent to the tooth is that part of the gingiva which attaches the connective tissue to the tooth surface fig. Junctional epithelium is derived from the reduced enamel epithelium during tooth development. Electron micrograph showing a rat junctional epithelium je.

The junctional epithelium is characterized by wide intercellular spaces, irregular outlines with thin cytoplasmic processes or concavities. The conversion of junctional epithelium to pocket epithelium is regarded as a hallmark in the development of periodontitis. However, they displayed an intact long junctional epithelial adhesion throughout the study, while control animals frequently showed ulceration of the sulcular epithelium. Therefore, the junctional epithelium plays an extremely important role, not only in attaching the tooth to the surrounding soft tissues but also in forming a tight biological seal, with. The junctional epithelium forms as the tooth crown erupts into the oral cavity. A large number of neutrophilic granulocytes leu within the intercellular spaces can be noted. Junctional epithelium part 3 ii stages of defence and. Pdf biological characteristics of junctional epithelium. Biological characteristics of the junctional epithelium. This attachment is continuously being renewed throughout life.

The junctional epithelium is attached to the tooth and forms a seal between the oral cavity and the underlying tissues. It forms a seal around the tooth and provides bacterial barricade by secreting different antimicrobial peptides. Analysis of differential expression of tight junction. It forms a band 23 mm wide around the tooth, and is approximately 1530 cells thick coronally and tapers to a single cell apically. The junctional epithelium is the epithelial component of the dentogingival unit that is in contact with the tooth surface. The conversion of the junctional to pocket epithelium, which is regarded as a hallmark in disease initiation, has been the focus of intense research in recent years. Visualization of junctional epithelial cell replacement by. It has two distinct basal laminas, the external basal lamina which is continuous with the basal lamina of the sulcular epithelium and attaches the junctional epithelium to the underlying.